Theses

Articles on TGFbeta signaling & ALK7

Guo_eLife2014


Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity

Tingqing Guo, Patricia Marmol, Annalena Moliner, Marie Björnholm, Chao Zhang, Kevan M Shokat and Carlos F Ibanez (2013)
eLife 2014;3:e03245
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Wu_Diabetologia2013
Differential regulation of pancreatic islet insulin secretion and Smad proteins by activin ligands

Wu, H., Mezghenna, K., Marmol, P., Guo, T., Moliner, A., Yang, S.N, Berggren, P.O. and Ibanez, C.F. (2014)
Diabetologia, 57: 148–156.
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Neuroendocrine control of female reproductive function by the activin receptor ALK7
Sandoval-Guzman, T., Göngrich, C., Moliner, A., Guo, T., Wu, H., Broberger, C. and Ibanez, C.F. (2012)
FASEB Journal, 26:4966-4976
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Growth/Differentiation Factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity
Andersson, O., Korach-Andre, M., Reissmann, E., Ibanez, C.F. (corresp. author) and Bertolino, P. (2008)
Proc. Natl. Acad. USA, 105, 7252-7256
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Activin B receptor ALK7 is a negative regulator of pancreatic b-cell function
Bertolino, P., Nilsson, R., Reissmann, E., Andersson, O., Berggren, P.-O. and Ibanez, C.F. (2008)
Proc. Natl. Acad. USA, 105, 7246-7251
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Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development

Andersson, O., Bertolino, P. and Ibanez, C.F. (2007)
Dev. Biol., 311, 500-511
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Growth differentiation factor 11 signals through the transforming growth factor beta receptor ALK5 to regionalize the anterior-posterior axis

Andersson, O., Reissmann, E. and Ibanez, C.F. (2006)
EMBO Rep., 7, 831-837
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Synergistic interaction between Gdf1 and Nodal during anterior axis development

Andersson, O., Reissmann, E., Jornvall, H. and Ibanez, C.F. (2006)
Dev. Biol., 293, 370-381
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ALK7, a receptor for Nodal, is dispensable for embryogenesis and left-right patterning in the mouse
Jornvall, H., Reissmann, E., Andersson, O., Mehrkash, M. and Ibanez, C.F. (2004)
Mol. Cell. Biol., 24, 9383-9389
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Recent evolutionary origin within the primate lineage of two pseudogenes with similarity to members of the TGF-b superfamily

Eketjall, E., Jornvall, H., Lonnerberg, P., Kobayashi, S. and Ibanez, C.F. (2004)
Cell. Mol. Life Sci., 61, 488-496
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Cross-talk between the Notch and TGF-b signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

Blokzijl, A., Dahlqvist, C., Reissmann, E., Falk, A., Moliner, A., Lendahl, U. and Ibanez, C. F. (2003)
J. Cell Biol. 163, 723-728
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Physical and functional interaction between GATA-3 and Smad3 allows TGF-bregulation of GATA target genes

Blokzijl, A., ten Dijke, P., and Ibanez, C. F. (2002)
Curr. Biol. 12, 35-45
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The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development
Reissmann, E., Jornvall, H., Blokzijl, A., Andersson, O., Chang, C., Minchiotti, G., Persico, M., Ibanez, C. F. (ca) and Brivanlou, A. H. (2001)
Genes & Dev 15, 2010-2022 [PDF]

The orphan receptor serine-threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line
Jornvall, H., Blokzijl, A., ten Dijke, P., and Ibanez, C. F. (2001)
J. Biol. Chem. 276, 5140-5146. [PDF]

A novel type I serine-threonine kinase receptor predominantly expressed in the adult central nervous system
Ryden, R., Imamura, T., Jornvall, H., Neveu, I., Trupp, M., Belluardo, N., Okadome, T., ten Dijke, P., and Ibanez, C. F. (1996)
J. Biol. Chem. 271, 30603-30609 [PDF]