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Adult function of GFRα1 in medial habenula neurons

Theses

ALK7 papers featured in Science-Business eXchange


Article in Science-Business eXchange (SciBX) features the two 2008 PNAS papers on ALK7 functions in metabolism from Carlos Ibanez lab. SciBX’s Lev Osherovich quizzes Carlos Ibanez on the latest findings from his team, with comments from Prof. Se-Jin Lee (Johns Hopkins University) and Jasbir Seehra (CSO, Acceleron Pharma Inc.).
SciBX 1, 6-7 (2008)
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Insights into GFRa1 Regulation of Neural Cell Adhesion Molecule (NCAM) Function from Structure-Function Analysis of the NCAM/GFRa1 Receptor

Sjostrand and Ibanez, C.F. (2008)
J. Biol. Chem., 283, 13792 -13798
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Dan's dissertation party


Stora Skuggan Wardshus, Stockholm
May 22, 2008

Here is Dan with external examiner Rudiger Klein taking revenge. Click on thumbnail for more images.

Dan Sjostrand


“GDNF and its receptors : A structure-function analysis of the NCAM-GDNF-GFRa1 complex and an examination of potential receptor candidates”
22 May, 2008

Abstract from KI website

External examiner:
Rudiger Klein
Max Planck Institute of Neurobiology
Martinsried, Germany

This thesis is based on the following papers:

I. Sjostrand, D., Carlsson, J., Paratcha, G,. Persson, B. and Ibanez, C.F. (2007) Disruption of the GDNF binding site in NCAM dissociates ligand binding and homophilic cell adhesion. J. Biol. Chem., 282, 12734-12740.[PDF]

II. Sjostrand and Ibanez, C.F. (2008) Insights into GFRa1 Regulation of Neural Cell Adhesion Molecule (NCAM) Function from Structure-Function Analysis of the NCAM/GFRa1 Receptor . J. Biol. Chem., 283, 13792 -13798.[PDF]

III. Abrescia, C., Sjostrand, D., Kjaer, S. and Ibanez, C.F. (2005) Drosophila RET contains an active tyrosine kinase and elicits neurotrophic activities in mammalian cells. FEBS Lett. 579, 3789-3796. [PDF]

IV. Sjostrand, D., Moliner, A. and Ibanez, C.F. (2008) GDNF signaling in GABAergic neurons of the medial ganglionic eminence: Roles of Met and ErbB4. Manuscript. Later published in 2011: J. Cell Sci., 124, 2797-2805. [PDF]


Growth/Differentiation Factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity
Andersson, O., Korach-Andre, M., Reissmann, E., Ibanez, C.F. (corresp. author) and Bertolino, P. (2008)
Proc. Natl. Acad. USA, 105, 7252-7256
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Activin B receptor ALK7 is a negative regulator of pancreatic b-cell function
Bertolino, P., Nilsson, R., Reissmann, E., Andersson, O., Berggren, P.-O. and Ibanez, C.F. (2008)
Proc. Natl. Acad. USA, 105, 7246-7251
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SVT interview with Carlos Ibanez on ALK7 findings


YouTube : SVT interview with Carlos Ibanez

Evening news from Sveriges Television features Carlos Ibanez speaking about the latest discoveries from his team on the roles of the ALK7 receptor in the control of insulin levels and fat deposition. From Rapport May 12, 2008