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New review explores the structure, evolution and function of the RET receptor tyrosine kinase

Cold Spring Harbour Perspectives in Biology has published Carlos Ibanez’s review on the structure and physiology of the RET receptor tyrosine kinase as part of their collection of reviews on receptor tyrosine kinases. RET, GDNF family ligands, and GFRα coreceptors activate signaling pathways involved in kidney and nervous system development. RET mutations cause Hirschsprung’s disease and at least four cancers. Read the full paper HERE.

 

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Structure and Physiology of the RET Receptor Tyrosine Kinase
Ibanez, C.F (2013)
Cold Spring Harb. Perspect. Biol., 5:a009134
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