Original articles


Sustained anti-obesity effects of life-style change and anti-inflammatory interventions after conditional inactivation of the activin receptor ALK7

Rajkamal Srivastava, Ee-Soo Lee, Eunice Sim, New Chih Shen and Carlos F. Ibáñez (2021)
The FASEB Journal. 2021;35:e21759

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Aging Cell 0.0:e13305

Age-related changes in hippocampal-dependent synaptic plasticity and memory mediated by p75 neurotrophin receptor

Lik-Wei Wong, Yee Song Chong, Wei Lin, Lilian Kisiswa, Eunice Sim, Carlos F. Ibáñez and Sreedharan Sajikumar (2020)
Aging Cell Vol 20, Issue 2, February 2021, e13305

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Inactive variants of death receptor p75NTR reduce Alzheimer’s neuropathology by interfering with APP internalization

Chenju Yi1, Ket Yin Goh, Lik-Wei Wong, Ajeena Ramanujan, Kazuhiro Tanaka, Sreedharan Sajikumar and Carlos F. Ibáñez (2020)
The EMBO Journal (2020) e104450

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Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7

Patricia Marmol-Carrasco, Favio Krapacher and Carlos F. Ibáñez (2020)
eLife 2020;9:e54721

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CD137 negatively affects “browning” of white adipose tissue during cold exposure

Rajkamal Srivastava, Annalena Moliner, Ee-Soo Lee, Emily Nickles, Eunice Sim, Chang Liu, Herbert Schwarz and Carlos F. Ibáñez

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ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons

Christina Göngrich, Favio Krapacher, Hermany Munguba, Diana Fernández-Suárez, Annika Andersson, Jens Hjerling-Leffler  and Carlos F. Ibáñez (2019)

Journal of Cell Biology (2019) DOI: 10.1083/jcb.201905002

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Cell Death and Disease, doi:10.1038/s41419-019-1970-x

MAG induces apoptosis in cerebellar granule neurons through p75NTR demarcating  granule layer/white matter boundary

Diana Fernández-Suárez, Favio A. Krapacher, Annika Andersson, Carlos F. Ibáñez and Lilian Kisiswa (2019)

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The p75 Neurotrophin Receptor Is an Essential Mediator of Impairments in Hippocampal-Dependent Associative Plasticity and Memory Induced by Sleep Deprivation

Lik-Wei Wong, Jason Y. Tann, Carlos F. Ibanez, and Sajikumar Sreedharan (2019)

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Abnormal TDP‐43 function impairs activity‐dependent BDNF secretion, synaptic plasticity, and cognitive behavior through altered Sortilin splicing

Jason Y Tann, Lik‐Wei Wong, Sreedharan Sajikumar, and Carlos F. Ibáñez (2019)
The EMBO Journal (2019) 10.15252/embj.2018100989

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A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTR Induces Melanoma Cell Death and Reduces Tumor Growth

Eddy T. H. Goh, Zhi Lin, Bo Young Ahn, Vanessa Lopes-Rodrigues, Ngoc Ha Dang, Shuhailah Salim, Bryan Berger, Brian Dymock, Donna L. Senger and Carlos F. Ibáñez (2018)
Cell Chemical Biology (2018) 25, 1485–1494

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RIP2 Gates TRAF6 Interaction with Death Receptor p75NTR to Regulate Cerebellar Granule Neuron Survival

Lilian Kisiswa, Diana Fernandez-Suarez, Maria Christina Sergaki and Carlos F. Ibáñez (2018)
Cell Reports Volume 24, Issue 4, p1013–1024, 24 July 2018

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Cell-autonomous role of GFRα1 in the development of olfactory bulb GABAergic interneurons

Sabrina Zechel, Diana Fernandez-Suarez and Carlos F. Ibáñez (2018)

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Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning

Maritina Sergaki, JC Lopez-Ramos, S Stagkourakis, A Gruart, C Broberger, JM Delgado-García and Carlos F. Ibáñez (2017)
Cell Reports volume 19, Issue 10, p1977-1986
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GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function

Maritina Sergaki and Carlos F. Ibáñez (2017)
Cell Reports volume 18, Issue 2, p367–379
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Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons

Sabrina Zechel, Yasushi Nakagawa and Carlos F. Ibáñez (2016)
eLife 2016
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(Supplemental information 31.6MB)

Death Domain Signaling by Disulfide-Linked Dimers of the p75 Neurotrophin Receptor Mediates Neuronal Death in the CNS

Kazuhiro Tanaka, Claire E. Kelly, Ket Yin Goh, Kim Buay Lim and Carlos F. Ibáñez (2016)
J Neurosci 36, 5587 (2016)
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Structural basis of death domain signaling in the  p75 neurotrophin receptor

Zhi Lin, Jason Y. Tann, Eddy T. H. Goh, Claire Kelly, Kim Buay Lim, Jianfang Gao and Carlos F. Ibáñez (2015)
eLife 2015;10.7554/eLife.11692
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Neuron-type-specific signaling by the p75NTR death receptor regulated by differential proteolytic cleavage
Annalisa Vicario, Lilian Kisiswa, Jason Y. Tann, Claire E. Kelly and Carlos F. Ibanez (2015)
J. Cell Sci. 2015, doi: 10.1242/​jcs.161745
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Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially-resolved RNA-seq

Sabrina Zechel, Pawel Zajac, Peter Lönnerberg, Carlos F Ibanez and Sten Linnarsson (2014)
Genome Biology.2014, 15:486
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Long-lasting benefits of ALK7 blockade in obesity

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