Inactive variants of death receptor p75NTR reduce Alzheimer’s neuropathology by interfering with APP internalization
Chenju Yi1, Ket Yin Goh, Lik-Wei Wong, Ajeena Ramanujan, Kazuhiro Tanaka, Sreedharan Sajikumar and Carlos F. Ibáñez (2020) The EMBO Journal (2020) e104450
Click on thumbnail to display PDF
Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7
Patricia Marmol-Carrasco, Favio Krapacher and Carlos F. Ibáñez (2020) eLife 2020;9:e54721
Click on thumbnail to display PDF
CD137 negatively affects “browning” of white adipose tissue during cold exposure
Rajkamal Srivastava, Annalena Moliner, Ee-Soo Lee, Emily Nickles, Eunice Sim, Chang Liu, Herbert Schwarz and Carlos F. Ibáñez
The p75 Neurotrophin Receptor Is an Essential Mediator of Impairments in Hippocampal-Dependent Associative Plasticity and Memory Induced by Sleep Deprivation
Lik-Wei Wong, Jason Y. Tann, Carlos F. Ibanez, and Sajikumar Sreedharan (2019)
A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTR Induces Melanoma Cell Death and Reduces Tumor Growth
Eddy T. H. Goh, Zhi Lin, Bo Young Ahn, Vanessa Lopes-Rodrigues, Ngoc Ha Dang, Shuhailah Salim, Bryan Berger, Brian Dymock, Donna L. Senger and Carlos F. Ibáñez (2018) Cell Chemical Biology (2018) 25, 1485–1494
Click on thumbnail to display PDF
RIP2 Gates TRAF6 Interaction with Death Receptor p75NTR to Regulate Cerebellar Granule Neuron Survival
Cell-autonomous role of GFRα1 in the development of olfactory bulb GABAergic interneurons
Sabrina Zechel, Diana Fernandez-Suarez and Carlos F. Ibáñez (2018) Biology Open 2018 7: bio033753
Click on thumbnail to display PDF
Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning
Maritina Sergaki, JC Lopez-Ramos, S Stagkourakis, A Gruart, C Broberger, JM Delgado-García and Carlos F. Ibáñez (2017) Cell Reports volume 19, Issue 10, p1977-1986
Click on thumbnail to display PDF
GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function
Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons
Sabrina Zechel, Yasushi Nakagawa and Carlos F. Ibáñez (2016) eLife 2016
Click on thumbnail to display PDF
(Supplemental information 31.6MB)
Death Domain Signaling by Disulfide-Linked Dimers of the p75 Neurotrophin Receptor Mediates Neuronal Death in the CNS
Kazuhiro Tanaka, Claire E. Kelly, Ket Yin Goh, Kim Buay Lim and Carlos F. Ibáñez (2016) J Neurosci 36, 5587 (2016)
Click on thumbnail to display PDF
Structural basis of death domain signaling in the p75 neurotrophin receptor
Zhi Lin, Jason Y. Tann, Eddy T. H. Goh, Claire Kelly, Kim Buay Lim, Jianfang Gao and Carlos F. Ibáñez (2015) eLife 2015;10.7554/eLife.11692 Click on thumbnail to display PDF
Neuron-type-specific signaling by the p75NTR death receptor regulated by differential proteolytic cleavage Annalisa Vicario, Lilian Kisiswa, Jason Y. Tann, Claire E. Kelly and Carlos F. Ibanez (2015) J. Cell Sci. 2015, doi: 10.1242/jcs.161745 Click on thumbnail to display PDF
Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially-resolved RNA-seq
Sabrina Zechel, Pawel Zajac, Peter Lönnerberg, Carlos F Ibanez and Sten Linnarsson (2014) Genome Biology.2014, 15:486
Click on thumbnail to display PDF
Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity
Tingqing Guo, Patricia Marmol, Annalena Moliner, Marie Björnholm, Chao Zhang, Kevan M Shokat and Carlos F Ibanez (2013) eLife 2014;3:e03245
Click on thumbnail to display PDF
Differential regulation of pancreatic islet insulin secretion and Smad proteins by activin ligands
Wu, H., Mezghenna, K., Marmol, P., Guo, T., Moliner, A., Yang, S.N, Berggren, P.O. and Ibanez, C.F. (2014) Diabetologia, 57: 148–156.
Click on thumbnail to display PDF