TGFbeta Superfamily Signaling in Adipocytes
Work at Carlos Ibanez laboratory focuses on understanding the functions and signaling mechanisms of growth factors and their receptors in nervous system function and metabolic regulation, for the development of better therapies to neurodegenerative and metabolic disorders. Carlos Ibanez is Professor at the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore.
A postdoctoral fellow is currently being recruited to advance research on growth factor receptor signaling and function in metabolic regulation of fat deposition, adipose tissue function, CNS regulation of metabolism, and obesity. In our latest paper, we reported that the sensitivity of fat cells to signals that increase the breakdown of fat is linked to the TGFbeta superfamily receptor ALK7. This discovery, published recently in eLife (http://elifesciences.org/content/3/e03245), suggests that ALK7 is a promising new target for strategies to treat human obesity.
We are seeking talented, innovative and enthusiastic researchers with a PhD awarded within the last 5 years to elucidate adipogenic and homeostatic functions of ALK4 and ALK7 receptors in adipose tissue to advance novel therapeutic opportunities. We will only consider candidates with documented expertise in studies of intracellular signaling pathways, with preference for TGFbeta superfamily signaling and molecular/cellular endocrinology. Candidates lacking expertise in this area will not be considered.
Applications, including CV, list of publications and statement of future interests should be sent to Prof. Carlos Ibanez (
). Applicants should arrange to have at least two confidential letters of reference sent independently by referees to this email address.
Funding is available for an initial period of 2 to 3 years, starting any time during 2015.
Deadline for application is March 1, 2015
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