UPDATE July 2019: The positions have been filled.
We are seeking talented and enthusiastic researchers with expertise in molecular and cellular neuroscience to advance investigations on the functions and mechanisms of growth factor receptor signaling and physiology in the nervous system. The research entails studies of different receptor systems in neuronal and nervous system function using molecular methods, cell culture models and mutant mice carrying specific mutations in these receptors.
Candidates will be accepted at the postdoctoral level with a PhD awarded preferably within the last 5 years. Strong and documented expertise in molecular and cellular methods of analysis as applied to studies of intracellular signaling in the area of neuroscience is an absolute requirement for consideration. Successful applicants shall be well versed in primary cultures of different neuronal populations from the mouse brain. The successful candidate is expected to be sufficiently independent to formulate questions, design experiments and perform research. For more information and publications, please look HERE in our lab website.
Applications, including CV, list of publications and statement of research interests should be sent by email to Prof. Carlos Ibanez ( ). Applicants should arrange to have at least two confidential letters of reference sent independently by referees to that email address.
Deadline for application is 20 June 2019.
Funding is available for an initial period of 3 years, with start during 2019.
UPDATE: The positions have been filled.
We are seeking talented and enthusiastic researchers with expertise in cell signaling, cell biology and mouse genetics to advance investigations on the functions and mechanisms of growth factor receptor signaling and physiology. The research entails studies of different receptor systems, including death receptor p75NTR, TGFbeta superfamily receptor ALK7 and neurotrophin receptor TrkB, using molecular methods, cell culture models and mutant mice carrying specific mutations in these receptors. Please refer to our recent list of publications in this areas.
Candidates will be accepted at the postdoctoral level with a PhD awarded preferably within the last 5 years. Strong and documented expertise in cellular, molecular and histological methods as applied to studies of mouse models in the areas of either neurobiology, metabolic regulation or cancer is a requirement for consideration. The successful candidate is expected to be sufficiently independent to formulate questions, design experiments and perform research.
We are recruiting fellows for our laboratories at the National University of Singapore and the Karolinska Institute in Stockholm, Sweden. Interested applicants can apply to both locations or just one. Work at the two laboratories is seamlessly integrated through joint lab meetings, common reagent and protocol records, and other cloud-based tools. Both sites provide exciting environments to pursue biomedical research at the highest level and a great opportunity to advance a career in science in exciting locations in Europe and Asia.
Applications, including CV, list of publications and statement of research interests should be sent to Prof. Carlos Ibanez ( or ). Applicants should arrange to have at least two confidential letters of reference sent independently by referees to either email address.
Applications will be considered as they arrive until the positions are filled. Interested applicants are strongly recommended to submit their applications as soon as possible. Funding is available for an initial period of 3 to 4 years, starting any time during 2018 or early 2019.
UPDATE 2017-05-29: The positions have been filled.
Postdoc/Research Fellows are being recruited to our NUS laboratory. We are seeking talented, innovative and enthusiastic researchers with a PhD awarded within the last 5 years.
Cell signaling
The successful candidate will have a strong background in studies of cell signaling using molecular, cellular and biochemical methods. The aim of the project is to elucidate mechanisms of differential signaling by death receptors through the NFkB, c-Jun kinase and RhoA GTPase pathways, among others, taking advantage of recent knowledge on structure-function relationships in this class of receptors as well as a large collection of mutants developed at our laboratory. Strong expertise in cell and molecular biology techniques is essential. Additional expertise in live cell imaging will also be an asset to the project.
Drug Discovery
The successful candidate will have a strong background in studies of intracellular signaling involving biochemical assays, gene reporter assays and microscopy techniques. The aim of the project is the identification and characterisation of novel small molecule modulators (inhibitors and activators) of growth factor receptor signaling taking advantage of a novel screening strategy developed in the laboratory based on recent knowledge on the mechanisms of activation and downstream signal propagation of death receptors and receptors of the TGFb superfamily. Strong expertise in cell and molecular biology techniques is essential. Additional expertise in small molecule screening and/or chemistry will also be an asset to the project.
Applications, including CV, list of publications and statement of future interests should be sent to Prof. Carlos Ibanez  . Applicants should arrange to have at least two confidential letters of reference sent independently by referees to this email address.
Funding is available for an initial period of 2 to 3 years, starting any time during 2017.
Deadline for the application is March 07, 2017.
UPDATE 01-06-2016: The position has been filled.
A Research Assistant/Associate is currently being recruited to our laboratory in the Centre for Life Sciences, National University of Singapore, Kent Ridge campus.
The successful candidate will be a dynamic, service-minded person, with a solid research background in molecular biology, tissue culture, histological techniques and/or mouse genetics methods. He/she will have a strong presence in the laboratory by assisting the group with experimental lab routines as well as conducting research together with other lab members or independently, including:
maintenance of mouse colonies and genotypinghistological studiesmolecular biology studiestissue culture studies
Applications including CV and names plus email addresses of three referees should be sent by email to Prof. Carlos Ibanez
Deadline: MAY 21st, 2016
UPDATE 2016-04-11: The position has been filled.
As part of a University-wide initiative on mechanisms of neuronal and synaptic injury in aging and neurodegenerative diseases, we are seeking talented and enthusiastic individuals to join our laboratory.
Carlos Ibanez is Professor at the Department of Physiology, Yong Loo Lin School of Medicine, National Univeristy of Singapore, and Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.
Under the direction of Prof. Carlos Ibanez, this project will focus on studies of the role of neurotrophin signaling in neurodegenerative diseases, with afocus on Alzheimer’s disease and dementias. This is an exciting opportunity for individuals who have received a doctoral degree within the past five years and with a strong background in cellular neurobiology. Other requirements include i) experience on mouse models, i i) experience in neurohistological methods, and iii) ability to work independently with precision and good organizational skills. Located on the Medical School campus of the National University of Singapore, there is close integration among the core laboratories of this strategic initiative. This provides for an exciting environment to pursue neuroscience research and a great opportunity in one of the most developed and exciting countries in the region.
Applications including CV and names plus email addresses of three referees should be sent by email to Prof. Carlos Ibanez .
Deadline: MARCH 31, 2016
A Research Assistant/Associate is currently being recruited to our laboratory in the Centre for Life Sciences, NUS campus. The successful candidate will be a dynamic, service-minded person, with a solid research background in molecular biology, tissue culture, histological techniques and/or mouse genetics methods. He/she will have a strong presence in the laboratory by assisting the group by with experimental lab routines, including maintenance of mouse colonies, genotyping, molecular biology and cell culture experiments, as well as conducting research together with other lab members or independently.
Work at the laboratory focuses on understanding the functions and signaling mechanisms of neuronal growth factors and their receptors in neural development, injury responses and metabolic regulation, for the development of better therapies to diseases of the nervous system and metabolism.
Applications including CV and names plus email addresses of three referees should be sent by email before August 20 to Prof. Carlos Ibanez .
UPDATE (09/2015): this position has been filled.
The Department of Physiology of the Yong Loo Lin School of Medicine at National University of Singapore has immediate opening for postdoctoral positions in Neuroscience, with specialization in Brain Vascular Biology. As part of a University-wide initiative on mechanisms of neuronal and synaptic injury in ageing and neurodegenerative diseases under the direction of Profs. Carlos Ibanez and Edward Koo, we are seeking talented and enthusiastic individuals to join our laboratories for postgraduate training.
Under the direction of Drs. Carlos Ibanez and Edward Koo, this project will focus on studies of the role of BDNF signaling in physiological and injury responses of cellular elements of the brain vascular system. More information about these laboratories can be found HERE and HERE. This is an exciting opportunity for individuals who have received a doctoral degree within the past five years and with a strong background in vascular biology or cellular neurobiology to receive further training in basic and translational studies in neurodegenerative diseases.
Requirements:
- Doctoral degree (PhD) in biological sciences
- Experience on mouse models and neuroscience research
- Experience on vascular biology studies is preferred
- Able to work independently with precision and possess good organizational skills
Our labs are located on the Medical School campus of the National University of Singapore. There is close integration among the core laboratories of this University supported strategic initiative in neuroscience. This provides for an exciting environment to pursue neuroscience research and a great opportunity for Singaporeans, Asian expats wishing to return somewhere closer home, or anyone interested in experiencing the Asian culture, in one of the most developed and exciting countries in the region.
Interested individuals should send application including cover letter, curriculum vitae, statement of research interests, and contact information, and provide names of three references to Prof. Carlos Ibanez .
Deadline is March 20, 2015.
TGFbeta Superfamily Signaling in Adipocytes
Work at Carlos Ibanez laboratory focuses on understanding the functions and signaling mechanisms of growth factors and their receptors in nervous system function and metabolic regulation, for the development of better therapies to neurodegenerative and metabolic disorders. Carlos Ibanez is Professor at the Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore.
A postdoctoral fellow is currently being recruited to advance research on growth factor receptor signaling and function in metabolic regulation of fat deposition, adipose tissue function, CNS regulation of metabolism, and obesity. In our latest paper, we reported that the sensitivity of fat cells to signals that increase the breakdown of fat is linked to the TGFbeta superfamily receptor ALK7. This discovery, published recently in eLife (http://elifesciences.org/content/3/e03245), suggests that ALK7 is a promising new target for strategies to treat human obesity.
We are seeking talented, innovative and enthusiastic researchers with a PhD awarded within the last 5 years to elucidate adipogenic and homeostatic functions of ALK4 and ALK7 receptors in adipose tissue to advance novel therapeutic opportunities. We will only consider candidates with documented expertise in studies of intracellular signaling pathways, with preference for TGFbeta superfamily signaling and molecular/cellular endocrinology. Candidates lacking expertise in this area will not be considered.
Our group at NUS has linked up with a network of researchers studying metabolism regulation in Singapore. This provides for an exciting environment to pursue metabolism research and a great opportunity for Singaporeans, Asian expats wishing to return somewhere closer home, or anyone interested in experiencing the Asian culture, in one of the most developed and exciting countries in the region.
Applications, including CV, list of publications and statement of future interests should be sent to Prof. Carlos Ibanez (). Applicants should arrange to have at least two confidential letters of reference sent independently by referees to this email address.
Funding is available for an initial period of 2 to 3 years, starting any time during 2015.
Deadline for application is March 1, 2015
A Research Assistant is currently being recruited to our NUS laboratory. The successful candidate will be a dynamic, service-minded person, with a solid research background in molecular biology, tissue culture, histological techniques and/or mouse genetics methods. He/she will have a strong presence in the laboratory by assisting the group by with experimental lab routines, including maintenance of mouse colonies, genotyping, molecular biology and histology, as well as conducting research together with other lab members or independently.
Work at the laboratory focuses on understanding the functions and signaling mechanisms of neuronal growth factors and their receptors in neural development, injury responses and metabolic regulation, for the development of better therapies to diseases of the nervous system and metabolism.
Applications including CV and names plus email addresses of three referees should be sent by email before September 5 to Prof. Carlos Ibanez .
A Research Assistant is currently being recruited to our NUS laboratory. The successful candidate will be a dynamic, service-minded person, with a solid research background in molecular biology, tissue culture, histological techniques and/or mouse genetics methods. He/she will have a strong presence in the laboratory by assisting the group by with experimental lab routines, including maintenance of mouse colonies, genotyping, molecular biology and cell culture experiments, as well as conducting research together with other lab members or independently.
Work at the laboratory focuses on understanding the functions and signaling mechanisms of neuronal growth factors and their receptors in neural development, injury responses and metabolic regulation, for the development of better therapies to diseases of the nervous system and metabolism.
Applications including CV and names plus email addresses of three referees should be sent by email before October 15 to Prof. Carlos Ibanez .
Postdoc/Research Fellows are currently being recruited to the new NUS laboratory. We are seeking talented, innovative and enthusiastic researchers with a PhD awarded within the last 10 years.
Systemic Cell Biology
The successful candidate will have a strong background in studies of cell signaling dynamics using biopysics and cell imaging methods such as fluorescence resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM), biosensors, total internal reflection fluorescence (TIRF), anisotropy and related time-resolved spectroscopy methods. Strong expertise in cell and molecular biology techniques is also essential.
iPS Cell Biology
The successful candidate will have a strong background in studies involving the generation and differentiation of Induced Pluripotent Stem Cells (iPSCs). The aim of the project is the characterization of death receptor signaling in human neurons derived from patients with neurodegenerative diseases. Additional experience in cell signaling and neuronal cell biology will also be an important asset.
Drug Discovery
The successful candidate will have a strong background in studies of intracellular signaling involving microscopy techniques, gene reporter assays and biochemical assays. The aim of the project is the identification of inhibitors to death receptor signaling taking advantage of recent knowledge on their mechanisms of activation and downstream signal propagation. Strong expertise in cell and molecular biology techniques is also essential.
Applications, including CV, list of publications and statement of future interests should be sent to Prof. Carlos Ibanez . Applicants should arrange to have at least two confidential letters of reference sent independently by referees to this email address.
Funding is available for an initial period of 2 to 3 years, starting any time during 2013.
Deadline for the application is February 15, 2013.
A Lab Manager is currently being recruited to our NUS laboratory. The successful candidate will be a dynamic, service-minded person, with a strong research background in cellular or molecular biology, neurobiology, metabolism and/or mouse genetics. He/she will assist the group with managing and organizing lab routines, protocols, orders, equipment and reagents. He/she will also have a strong presence in the laboratory by conducting research together with other lab members or independently.
Work at the laboratory will focus on understanding the functions and signaling mechanisms of neuronal growth factors and their receptors in neural development, injury responses and metabolic regulation, for the development of better therapies to diseases of the nervous system and metabolism.
Applications should be sent by email before January 31 to .
PhD students, postdoctoral fellows and lab technicians are being recruited for the new NUS laboratory.
Work at the laboratory will focus on understanding the functions and signaling mechanisms of neuronal growth factors in neural development, injury responses and metabolic regulation, for the development of better therapies to diseases of the nervous system and metabolism.
Candidates with expertise in cellular, molecular or structural biology, neurobiology, metabolism and mouse genetics are encouraged to apply.
For contact and information, please write to Carlos Ibanez at .
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