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PKC-mediated RhoGDI interaction with p75NTR JUX domain


New postdoc fellow joins KI group to develop medicinal chemistry work on candidate compounds

Michael Saleeb obtained a PhD in Organic Chemistry at Umeå University in Sweden in September 2018, under the direction of Prof. Mikael Elofsson. His PhD thesis was focused on the identification of novel antibacterial compounds against Chlamydia trachomatis & Pseudomonas aeruginosa infections. During his PhD, Michael developed expertise in chemical synthesis including C-C and C-X metal-catalyzed cross coupling, C-H insertion reactions, various heterocyclic and polyphenol syntheses. Michael  joins our KI team to develop medicinal chemistry approaches to modify and improve on candidate small molecules capable of modulating the activities of various receptors, including our recently discovered compounds targeting p75NTR, based on our article in Cell Chemical Biology.