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Human ACVR1C missense variants that correlate with altered body fat distribution produce metabolic alterations of graded severity in knock-in mutant mice
Pawanrat Tangseefa , Hong Jin, Houyu Zhang, Meng Xie & Carlos F. Ibáñez
Molecular Metabolism (2024) 10.1016/j.molmet.2024.101890
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Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors
Ee-Soo Lee , Tingqing Guo, Raj Kamal Srivastava, Assim Shabbir & Carlos F. Ibáñez
The Journal of Biological Chemistry (2022) doi.org/10.1016/j.jbc.2022.102716
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Convergent dopamine and ALK4 signaling to PCBP1 controls FosB alternative splicing and cocaine behavioral sensitization
Favio A Krapacher , Diana Fernandez-Suarez, Annika Andersson , Alvaro Carrier-Ruiz & Carlos F. Ibáñez (2021)
The EMBO Journal (2022) e110721
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Sustained anti-obesity effects of life-style change and anti-inflammatory interventions after conditional inactivation of the activin receptor ALK7
Rajkamal Srivastava, Ee-Soo Lee, Eunice Sim, New Chih Shen and Carlos F. Ibáñez (2021)
The FASEB Journal. 2021;35:e21759
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 The FEBS Journal 0.0:null-null
Regulation of metabolic homeostasis by the TGF-b superfamily receptor ALK7
Ibanez, C.F (2021)
FEBS Journal, June 2021, doi:10.1111/febs.16090
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 Aging Cell 0.0:e13305
Age-related changes in hippocampal-dependent synaptic plasticity and memory mediated by p75 neurotrophin receptor
Lik-Wei Wong, Yee Song Chong, Wei Lin, Lilian Kisiswa, Eunice Sim, Carlos F. Ibáñez and Sreedharan Sajikumar (2020)
Aging Cell Vol 20, Issue 2, February 2021, e13305
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Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7
Patricia Marmol-Carrasco, Favio Krapacher and Carlos F. Ibáñez (2020)
eLife 2020;9:e54721
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ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons
Christina Göngrich, Favio Krapacher, Hermany Munguba, Diana Fernández-Suárez, Annika Andersson, Jens Hjerling-Leffler and Carlos F. Ibáñez (2019)
Journal of Cell Biology (2019) DOI: 10.1083/jcb.201905002
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Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity
Tingqing Guo, Patricia Marmol, Annalena Moliner, Marie Björnholm, Chao Zhang, Kevan M Shokat and Carlos F Ibanez (2013)
eLife 2014;3:e03245
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Differential regulation of pancreatic islet insulin secretion and Smad proteins by activin ligands
Wu, H., Mezghenna, K., Marmol, P., Guo, T., Moliner, A., Yang, S.N, Berggren, P.O. and Ibanez, C.F. (2014)
Diabetologia, 57: 148–156.
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Neuroendocrine control of female reproductive function by the activin receptor ALK7
Sandoval-Guzman, T., Göngrich, C., Moliner, A., Guo, T., Wu, H., Broberger, C. and Ibanez, C.F. (2012)
FASEB Journal, 26:4966-4976
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Growth/Differentiation Factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity
Andersson, O., Korach-Andre, M., Reissmann, E., Ibanez, C.F. (corresp. author) and Bertolino, P. (2008)
Proc. Natl. Acad. USA, 105, 7252-7256
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Activin B receptor ALK7 is a negative regulator of pancreatic b-cell function
Bertolino, P., Nilsson, R., Reissmann, E., Andersson, O., Berggren, P.-O. and Ibanez, C.F. (2008)
Proc. Natl. Acad. USA, 105, 7246-7251
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Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development
Andersson, O., Bertolino, P. and Ibanez, C.F. (2007)
Dev. Biol., 311, 500-511
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Growth differentiation factor 11 signals through the transforming growth factor beta receptor ALK5 to regionalize the anterior-posterior axis
Andersson, O., Reissmann, E. and Ibanez, C.F. (2006)
EMBO Rep., 7, 831-837
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Synergistic interaction between Gdf1 and Nodal during anterior axis development
Andersson, O., Reissmann, E., Jornvall, H. and Ibanez, C.F. (2006)
Dev. Biol., 293, 370-381
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ALK7, a receptor for Nodal, is dispensable for embryogenesis and left-right patterning in the mouse
Jornvall, H., Reissmann, E., Andersson, O., Mehrkash, M. and Ibanez, C.F. (2004)
Mol. Cell. Biol., 24, 9383-9389
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Recent evolutionary origin within the primate lineage of two pseudogenes with similarity to members of the TGF-b superfamily
Eketjall, E., Jornvall, H., Lonnerberg, P., Kobayashi, S. and Ibanez, C.F. (2004)
Cell. Mol. Life Sci., 61, 488-496
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Cross-talk between the Notch and TGF-b signaling pathways mediated by interaction of the Notch intracellular domain with Smad3
Blokzijl, A., Dahlqvist, C., Reissmann, E., Falk, A., Moliner, A., Lendahl, U. and Ibanez, C. F. (2003)
J. Cell Biol. 163, 723-728
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Physical and functional interaction between GATA-3 and Smad3 allows TGF-bregulation of GATA target genes
Blokzijl, A., ten Dijke, P., and Ibanez, C. F. (2002)
Curr. Biol. 12, 35-45
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The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development
Reissmann, E., Jornvall, H., Blokzijl, A., Andersson, O., Chang, C., Minchiotti, G., Persico, M., Ibanez, C. F. (ca) and Brivanlou, A. H. (2001)
Genes & Dev 15, 2010-2022 [PDF]
The orphan receptor serine-threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line
Jornvall, H., Blokzijl, A., ten Dijke, P., and Ibanez, C. F. (2001)
J. Biol. Chem. 276, 5140-5146. [PDF]
A novel type I serine-threonine kinase receptor predominantly expressed in the adult central nervous system
Ryden, R., Imamura, T., Jornvall, H., Neveu, I., Trupp, M., Belluardo, N., Okadome, T., ten Dijke, P., and Ibanez, C. F. (1996)
J. Biol. Chem. 271, 30603-30609 [PDF]
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