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PKC-mediated RhoGDI interaction with p75NTR JUX domain

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Postdoc position in pancreatic islet biology

A postdoctoral position is available for experienced molecular endocrinologists to join our team investigating the role of growth factor signaling in metabolic regulation using mouse models carrying mutations in the Activin receptors ALK7 and ALK4, novel regulators of glucose homeostasis and energy balance (see Bertolino et al. and Andersson et al., PNAS 2008). The aim of the project is to understand the functional role of activin signaling through ALK7 and ALK4 in pancreatic islets and its contribution to the regulation of insulin secretion and glucose homeostasis. In order to tackle these questions, we have recently generated conditional and chemically inducible mutant mouse lines which will be available for analysis at the start of the project.

We are seeking a talented, innovative and enthusiastic researcher with a PhD awarded within the last 4 years. Highly motivated candidates with a genuine interest in metabolic regulation and mouse genetics are encouraged to apply. Priority will be given to candidates with strong expertise in pancreatic islet biology and studies of insulin secretion and glucose homeostasis.

Applications, including CV, list of publications and statement of future interests should be sent to . Applicants should arrange to have at least two confidential letters of reference to be sent directly by referees.

Funding is available for an initial period of 2 years, starting any time during 2012.

Review of applications will begin immediately and will continue until the position is filled.

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