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PKC-mediated RhoGDI interaction with p75NTR JUX domain

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Postdoctoral position in medicinal chemistry for drug discovery in death receptor signaling

UPDATE : the position has been filled.

We are seeking a talented and enthusiastic researcher with expertise in medicinal chemistry and chemical biology to advance drug discovery efforts and investigations on death receptor signaling and physiology in cancer and neuronal cells. The research entails medicinal chemistry studies on small molecules targeting the p75NTR death receptor identified in our ongoing screens, with the objective to improve the pharmacokinetic and biological properties of chemical leads. Please see Goh et al. (2018) Cell Chemical Biology 25, 1485–1494 for a representative publication of this work.

Candidates will be accepted at the postdoctoral level with a PhD awarded within the last 3 years. Strong and documented expertise in medicinal chemistry and chemical biology is a requirement for consideration. The successful candidate is expected to be sufficiently independent to formulate questions, design experiments and perform research. Excellent command of the English language is reuqired.

Applications, including CV (no diploma copies needed at this time please), list of publications and statement of research interests should be sent by email to Prof. Carlos Ibanez () and through the job web page of Karolinska Institute. Applicants should arrange to have at least two confidential letters of reference sent independently by referees to this email address. Funding is available for an initial period of 3 to 4 years.

Deadline for application is 29 September 2019.

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